気になる vs 気にする — which one is the intransitive/uncontrollable one?

I keep mixing these up. 「彼のことが気になる」and 「彼のことを気にする」both seem to mean 'I'm bothered by/thinking about him,' but one takes が and the other を. Is there a real difference in nuance, or mostly just grammatical structure?
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沐學 Mizuru